Information for UK-based patients who have been prescribed RYBELSUS®

Frequently asked questions

This page contains some answers to commonly asked questions about RYBELSUS®

Always consult your doctor or treating healthcare professional for any specific question you may have when taking your medication

Please always ensure that you read the Patient Information Leaflet↗ accompanying your medication. Please refer to the Patient Information Leaflet↗ for information about taking RYBELSUS® including what you need to know before you start, dosing instructions and a list of possible side effects


How to store RYBELSUS® ?


Store in the original packaging in order to protect from light and moisture. This medicine does not require any special temperature storage conditions. Keep this medicine out of the sight and reach of children

Why is it important to take my tablet on an empty stomach?


Taking RYBELSUS® on an empty stomach is important, as any kind of food, beverage, or oral medication may reduce the amount of RYBELSUS® entering your blood stream and therefore not be as effective. This is why it is recommended to wait at least 30 minutes after taking RYBELSUS® before having any food, drink or taking any other oral medicine

Can I take RYBELSUS® with anything other than water?


No. The effectiveness of RYBELSUS® has not been studied with any other type of drink

Why is it important to wait at least 30 minutes before eating, drinking, or taking other oral medication?


RYBELSUS® may not work properly if you eat, drink, or take other oral medication within 30 minutes after taking RYBELSUS®

Will it interfere with my current medications?


Tell your doctor, nurse, or pharmacist if you are taking, have recently taken or might take any other medicine to see if they are okay to take with RYBELSUS®. Refer to the RYBELSUS® Patient Information Leaflet↗ for specific information, in particular if you are using medicines containing levothyroxine which is used for thyroid disease, warfarin or similar medicines taken by mouth to reduce blood clotting (oral anti-coagulants) or insulin

Will I experience hypoglycaemia?


Low blood sugar (hypoglycaemia) can occur with RYBELSUS® particularly if you are taking any blood sugar-lowering medications, like insulin and/or sulfonylureas. Signs and symptoms of hypoglycaemia may include: cold sweats, headache, fast heartbeat, feeling sick and/or hungry, dizziness, feeling sleepy and/or weak, nervousness and shaking

If you think you are experiencing hypoglycaemia while taking RYBELSUS®, contact your doctor or nurse for advice

What should I do if I forgot to take a dose?


If you forgot to take a dose, the missed dose should be skipped. The next dose should be taken the following day. Do not take a double-dose

Do I need to take my tablet at the same time every day?


It’s important to get into a routine and take RYBELSUS® on an empty stomach, upon waking, but it does not need to be at the same time every day

Does RYBELSUS® contain sodium?


Yes, RYBELSUS® contains 23 mg sodium (main component of cooking/table salt) in each tablet. This is equivalent to 1% of the recommended maximum daily dietary intake of sodium for an adult.

Possible side effects

Stay informed about possible side effects

Dosing plan

Take your dose as prescribed by your doctor

UK21RYB00236 | November 2021